Abstract
Pattern of maternal vaginal flora in labor and its effect on the newborn
Highlights
The new-born period is one of the phases of increased vulnerability to infections and this threat begins right from the intrauterine period and passage through the maternal birth canal.Neonatal sepsis is the single most important cause of neonatal morbidity and mortality in the community, accounting for around 30- 50%
This study showed a statistically significant association between features of sepsis in babies and maternal vaginal colonization
This study shows that maternal vaginal colonisation has significant association with neonatal sepsis
Summary
The new-born period is one of the phases of increased vulnerability to infections and this threat begins right from the intrauterine period and passage through the maternal birth canal.Neonatal sepsis is the single most important cause of neonatal morbidity and mortality in the community, accounting for around 30- 50%. Neonatal deaths in developing countries were caused by infections (42%), asphyxia and birth trauma (29%), preterm babies and low birth weight (10%), congenital abnormalities (14%) and other causes (4%). Neonatal sepsis is the most important cause of morbidity and mortality in developing countries. This study showed a statistically significant association between features of sepsis in babies and maternal vaginal colonization. Of the 60 babies with suspected sepsis, 40 had positive blood culture which is the gold standard investigation for sepsis All of these culture positive babies i.e all 40(100%) had maternal colonization with a statistically significant association. Conclusion: This study shows that maternal vaginal colonisation has significant association with neonatal sepsis. Finding the organism in the maternal vaginal flora and treating it as per sensitivity might result less cases of neonatal sepsis
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