Pattern of Glucose and Lipid Profile in Obese Diabetic and Non-diabetic Subjects in the Population of Rawalpindi

Abstract

Obesity is the fifth leading risk for global deaths, which may lead to type 2 diabetes mellitus. This study was planned to see the glucose and lipid profile in obese diabetic and non-diabetic subjects in the local population of Rawalpindi. We planned to study the variation of glucose and lipid profile in obese diabetic and non-diabetic subjects in the local population of Rawalpindi. This case control study was conducted at chemical pathology Laboratory, Holy Family Hospital and Benazir Bhutto Hospital, Rawalpindi. Non-probability purposive sampling was done on 100 subjects out of whom 50 were obese diabetic (21 males and 29 females), and 50 were obese non diabetic (23 males and 27 females) individuals from the general population of Rawalpindi. Blood sample was analyzed for estimation of FPG (fasting plasma glucose) and lipid profile. The t-test was applied and p-Value of <0.005 was considered significant. The study showed that the FPG of obese diabetics was higher than obese non-diabetic (164.7±29 and 92.9±10.5mg/dl) with a p-Value is <0.001. Total cholesterol was (204.3±17.4 and 161.6±38.1mg/dl) and a p-Value is <0.001. Triglycerides (TG) was (216±34 and 146±57mg/dl) and a p-Value is <0.001. HDL (high density lipoproteins) was (33±3.5 and 38±5.4mg/dl) and a p-Value is <0.001). LDL (low density lipoproteins) was (127±16 and 94±33mg/dl) and a p-Value is <0.001, respectively. No significant difference in BMI (body mass index) was observed between obese Diabetic and non-Diabetics and this was (29.2±6 and 30.3±4.5 kg/m2) and a p-Value is <0.279. It is concluded that difference in the levels of fasting plasma glucose and lipid profile is highly significant in both obese diabetic and non-diabetic individuals.