Pattern of Changes in Semen Characteristics in Subfertile Males of South Asian Subcontinent: Analysis of 1,000 Semen Samples

Abstract

ABSTRACT Aim To investigate and compare whether semen quality has changed in South Asian subfertile males attending three different infertility units. Objectives To characterize the semen parameters of subfertile men in South Asian region and to study the prevalence of abnormal semen parameters of subfertile males of South Asian subcontinent. Materials and methods Study period — January 2014 to December 2014. Setting: Centre for Assisted Reproduction, BIRDEM, Dhaka, Bangladesh Malhotra Nursing Home, Agra, Uttar Pradesh, India Lahore Institute of Fertility and Endocrinology, Lahore, Punjab, Pakistan The possible decline in semen parameters related to male fertility was evaluated by determining the volume, sperm count, motility, viability, and morphology in individuals attending infertility clinics. WHO 2004 initially and then WHO 2010 criteria were used to analyze the semen sample. Results There was no significant age difference among the participants from three different countries. There was significant increase rate of azoopsermia in all the population groups especially in Bangladeshi population. Necrozospermia (100%) immotile sperm is higher in Pakistani populations compare to Bangladeshis and Indians. Normal sperm parameters (Normozoospermia) rate is compatible in Pakistani and Indian male but lower rate is noted in Bangladeshi population. No significant changes were noted in oligozospermia group but significant changes in asthenozospermia noted in Bangladeshi population compare two other two countries Statistical analysis Statistical analysis were performed by using Statistical Software Package (SAS) version 9.1.3 (SAS Institute Inc., Cary, NC, USA). Conclusion Our finding suggested that the values of sperm parameters were in agreement with WHO criteria, significantly different in subfertile men of this region. A further study with good quality collaborative long term research should be carried out, including aspects such as semen quality, reproductive hormones and xenobiotics as well as a strict definition of fecundity in this region is needed. How to cite this article Mahmud N, Malhotra N, Malhotra J, Khan HL. Pattern of Changes in Semen Characteristics in Subfertile Males of South Asian Subcontinent: Analysis of 1,000 Semen Samples. J South Asian Feder Obst Gynae 2016;8(2):145-148.