Patients with New-Onset Tumor of Severe Coronary Artery Disease May be at a Higher Risk of Arrhythmia.

Palisha Alimu,Huatao Zhou,Dezhi Yang,Huiping Guo,Yan Wu,Hao Zhou

doi:10.1155/2021/1948624

Abstract

Background Arrhythmia is one of the causes of death in severe coronary artery disease patients who also suffered from cancer. Our research aims to compare the incidence of arrhythmia between severe coronary artery disease patient with and without new-onset tumor. Methodology. We enrolled 79 patients (December 2019–December 2020) with severe coronary artery disease in this study, and 40 of them were complicated with new-onset tumor. The details of all subjects were thoroughly obtained; the laboratory tests were implemented including creatinine before coronary angiography. The appraisal of the severity of coronary artery disease was applied by Gensini score. The cardiac inspection includes UCG, 12-lead ECG, and Holter monitor. Results Among them, there were 40 patients in the experimental group and 39 patients in the control group. The difference at the baseline between the two sets of figures was not statistically significant (P > 0.05). The incidence of arrhythmia between the two groups was statistically significant (P < 0.05). Conclusions The incidence of arrhythmia in severe coronary artery disease patients who were complicated with new-onset tumor was higher than that in patients with severe coronary artery disease alone, and attention should be paid to arrhythmia before tumor treatment.

Highlights

Mortality rates of coronary heart disease and tumors have declined, they remain the leading causes of death in humans [1, 2]
We observed in our study that the incidence of arrhythmia in the severe coronary artery disease group with new-onset tumor was 60% and another group was 25.6%
The association of cardiac arrhythmia with coronary artery disease (CAD) or cancer has long been paid attention to, there still exists little research regarding the relation between the severity of CAD and the prevalence of cardiac arrhythmia in new-onset cancer patients. e etiology of arrhythmias in cancer patients has not been clear yet, despite the anticancer therapy factor, which may be a result of the direct cardiac involvement of the primary cancer or metastasis to heart [8, 9]

Summary

Introduction

Mortality rates of coronary heart disease and tumors have declined, they remain the leading causes of death in humans [1, 2]. Arrhythmia is very common in patients with coronary heart disease complicated with tumor [3]. Few studies had been conducted on arrhythmia in cancer patients complicated by severe coronary artery disease. Arrhythmia is one of the causes of death in severe coronary artery disease patients who suffered from cancer. Our research aims to compare the incidence of arrhythmia between severe coronary artery disease patient with and without new-onset tumor. We enrolled 79 patients (December 2019–December 2020) with severe coronary artery disease in this study, and 40 of them were complicated with new-onset tumor. E incidence of arrhythmia in severe coronary artery disease patients who were complicated with new-onset tumor was higher than that in patients with severe coronary artery disease alone, and attention should be paid to arrhythmia before tumor treatment Conclusions. e incidence of arrhythmia in severe coronary artery disease patients who were complicated with new-onset tumor was higher than that in patients with severe coronary artery disease alone, and attention should be paid to arrhythmia before tumor treatment

Methods

Results

Conclusion