Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)

Manuela Salvucci,Jochen H M Prehn,Nyree Crawford,Katie Stott,Daniel B Longley,Susan Bullman

doi:10.1136/gutjnl-2021-325193

Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)

Manuela Salvucci, Jochen H M Prehn + Show 4 more

Open Access

https://doi.org/10.1136/gutjnl-2021-325193

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Journal: Gut	Publication Date: Sep 8, 2021
Citations: 34	License type: open-access

Affiliation: Royal College of Surgeons in Ireland, Queen's University Belfast, Fred Hutch Cancer Center

#Infiltration Of M1 Macrophages #Consensus Molecular Subtyping + Show 8 more

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Abstract

ObjectivesTranscriptomic-based subtyping, consensus molecular subtyping (CMS) and colorectal cancer intrinsic subtyping (CRIS) identify a patient subpopulation with mesenchymal traits (CMS4/CRIS-B) and poorer outcome. Here, we investigated the relationship between prevalence...

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