Patients Infected with HIV Type 1 Subtype CRF01_AE and Failing First-Line Nevirapine- and Efavirenz-Based Regimens Demonstrate Considerable Cross-Resistance to Etravirine

Abstract

AIDS Research and Human RetrovirusesVol. 26, No. 6 Letter to the EditorPatients Infected with HIV Type 1 Subtype CRF01_AE and Failing First-Line Nevirapine- and Efavirenz-Based Regimens Demonstrate Considerable Cross-Resistance to EtravirineWeerawat Manosuthi, David M. Butler, Wasun Chantratita, Chonlaphat Sukasem, Douglas D. Richman, and Davey M. SmithWeerawat ManosuthiBamrasnaradura Infectious Diseases Institute, Ministry of Public Health, Nonthaburi, Thailand.Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.Search for more papers by this author, David M. ButlerUniversity of California San Diego, La Jolla, California.Search for more papers by this author, Wasun ChantratitaFaculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.Search for more papers by this author, Chonlaphat SukasemFaculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.Search for more papers by this author, Douglas D. RichmanUniversity of California San Diego, La Jolla, California.Veterans Affairs San Diego Healthcare System, San Diego, California.Search for more papers by this author, and Davey M. SmithUniversity of California San Diego, La Jolla, California.Veterans Affairs San Diego Healthcare System, San Diego, California.Search for more papers by this authorPublished Online:20 Jun 2010https://doi.org/10.1089/aid.2009.0107AboutSectionsView articleView Full TextPDF/EPUB ToolsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View articleFiguresReferencesRelatedDetailsCited ByGlobal Comparison of Drug Resistance Mutations After First-Line Antiretroviral Therapy Across Human Immunodeficiency Virus-1 Subtypes3 November 2015 | Open Forum Infectious Diseases, Vol. 3, No. 2High prevalence of PI resistance in patients failing second-line ART in Vietnam11 December 2015 | Journal of Antimicrobial Chemotherapy, Vol. 71, No. 3A simian-human immunodeficiency virus carrying the rt gene from Chinese CRF01_AE strain of HIV is sensitive to nucleoside reverse transcriptase inhibitors and has a highly genetic stability in vivoMicrobes and Infection, Vol. 16, No. 6Extensive Drug Resistance in HIV-Infected Cambodian Children Who Are Undetected as Failing First-Line Antiretroviral Therapy by WHO 2010 Guidelines Mia Coetzer, Benjamin Westley, Allison DeLong, Chhraing Tray, Dim Sophearin, Eric Nerrienet, Leeann Schreier, and Rami Kantor13 June 2013 | AIDS Research and Human Retroviruses, Vol. 29, No. 7The Potential Cost and Benefits of Raltegravir in Simplified Second-Line Therapy among HIV Infected Patients in Nigeria and South Africa15 February 2013 | PLoS ONE, Vol. 8, No. 2High Plasma Efavirenz Concentration and CYP2B6 Polymorphisms in Thai HIV-1 InfectionsDrug Metabolism and Pharmacokinetics, Vol. 28, No. 5Unusual Insertion and Deletion at Codon 67 and 69 of HIV Type 1 Subtype C Reverse Transcriptase Among First-Line Highly Active Antiretroviral Treatment-Failing South Indian Patients: Association with Other Resistance Mutations Shanmugam Saravanan, Vidya Madhavan, Rami Kantor, Sathasivam Sivamalar, Selvamurthi Gomathi, Sunil S. Solomon, Nagalingeswaran Kumarasamy, Davey M. Smith, Robert T. Schooley, Suniti Solomon, and Pachamuthu Balakrishnan21 November 2012 | AIDS Research and Human Retroviruses, Vol. 28, No. 12Antiviral Drug Resistance and the Need for Development of New HIV-1 Reverse Transcriptase InhibitorsAntimicrobial Agents and Chemotherapy, Vol. 56, No. 10The Need for Development of New HIV-1 Reverse Transcriptase and Integrase Inhibitors in the Aftermath of Antiviral Drug ResistanceScientifica, Vol. 2012Short Communication Prevalence of Susceptibility to Etravirine by Genotype and Phenotype in Samples Received for Routine HIV Type 1 Resistance Testing in the United States Gaston Picchio, Johan Vingerhoets, Lotke Tambuyzer, Eoin Coakley, Mojgan Haddad, and James Witek29 November 2011 | AIDS Research and Human Retroviruses, Vol. 27, No. 12Genotypic Impact of Prolonged Detectable HIV Type 1 RNA Viral Load after HAART Failure in a CRF01_AE-Infected Cohort Maria Zolfo, Jonathan M. Schapiro, Vichet Phan, Olivier Koole, Sopheak Thai, Marc Vekemans, Katrien Fransen, and Lutgarde Lynen27 June 2011 | AIDS Research and Human Retroviruses, Vol. 27, No. 7Selection of nonnucleoside reverse transcriptase inhibitor-associated mutations in HIV-1 subtype C: evidence of etravirine cross-resistanceAIDS, Vol. 25, No. 8Reverse transcriptase mutation K65N confers a decreased replication capacity to HIV-1 in comparison to K65R due to a decreased RT processivityVirology, Vol. 414, No. 1Assessments of HIV Drug Resistance Mutations in Resource-Limited Settings15 April 2011 | Clinical Infectious Diseases, Vol. 52, No. 8Characterization of the E138K Resistance Mutation in HIV-1 Reverse Transcriptase Conferring Susceptibility to Etravirine in B and Non-B HIV-1 SubtypesAntimicrobial Agents and Chemotherapy, Vol. 55, No. 2 Volume 26Issue 6Jun 2010 InformationCopyright 2010, Mary Ann Liebert, Inc.To cite this article:Weerawat Manosuthi, David M. Butler, Wasun Chantratita, Chonlaphat Sukasem, Douglas D. Richman, and Davey M. Smith.Patients Infected with HIV Type 1 Subtype CRF01_AE and Failing First-Line Nevirapine- and Efavirenz-Based Regimens Demonstrate Considerable Cross-Resistance to Etravirine.AIDS Research and Human Retroviruses.Jun 2010.609-611.http://doi.org/10.1089/aid.2009.0107Published in Volume: 26 Issue 6: June 20, 2010Online Ahead of Print:May 27, 2010PDF download