Abstract
<b>Introduction:</b> Implementation of patient-reported outcome measures (PROMs) may augment quality of care in lung cancer, but further data are needed to validate their exact clinical relevance in routine clinical practice. <b>Aim:</b> We herein aimed to investigate the effect of a PROMs tool on palliative care outcomes and overall quality of life (QoL) in patients with advanced-stage non-small cell lung cancer (NSCLC). <b>Methods:</b> 100 adult patients with stage IV NSCLC, diagnosed and treated at the Oncology Unit of “Sotiria” Athens General Hospital, were prospectively enrolled and randomized into two groups: the control group (routine supportive care) and the experimental group (supportive care guided by PROMs). Both groups completed the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire‐Lung Cancer 13 (QLQ‐LC13) at two consecutive assessments/time points, i.e. before administration of two consecutive treatments. <b>Results:</b> A statistically significant increase in the subscales "Physical Functionality" (p = 0.047) and "Emotional Functionality" (p = 0.002), as well as a decrease in the subscales "Fatigue" (p <0.001), "Nausea and Vomiting" (p <0.001), "Pain" (p = 0.002), "Sleep Disorders" (p < 0.001), "Loss of appetite" (p <0.001) and "Constipation" (p <0.001) were observed from the 1st to the 2nd measurement in the experimental group. A trend towards improved overall QoL was also noted in the experimental group, albeit without reaching statistical significance. <b>Conclusions:</b> Providing supportive care according to lung-cancer specific PROMs may improve symptomatic control in advanced NSCLC.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.