Abstract
Patient-reported outcomes are increasingly considered as endpoints for clinical studies. Instruments for measuring patient-reported outcomes range from simple assessments of discrete symptoms or signs to complex measures addressing multidimensional constructs such as health-related quality of life. While generic measures are designed to be applicable across a wide range of clinical conditions, disease- or population-specific instruments address health problems which are relevant for a particular disease or target group. Patient-reported outcomes can provide supplementary information from the patient's perspective when clinical endpoints are the primary focus of a study. As predictors and mediators of clinical outcomes they may contribute to the understanding of how patients benefit from treatment. They are included as primary endpoints when treatment effects comprise subjective phenomena such as pain, fatigue or psychological well-being. Current research activities in the field of patient-reported outcomes include the development of new (disease-specific) instruments, head-to-head comparisons of psychometric properties of measures, analysis of the context-dependence of results, and application of patient-reported outcomes in clinical practice.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Zeitschrift fuer Evidenz, Fortbildung und Qualitaet im Gesundheitswesen
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.