Abstract
Background: Hospital drug therapy has the potential for incidents, thus it is necessary to identify situations that may compromise patient safety.Objective: To investigate potential drug-drug interactions caused by the overlapping of medications planned by nurses in the patients’ prescriptions at a hospital inpatient unit.Methodology: Descriptive, cross-sectional study of documentary analysis with a quantitative approach, of 260 prescriptions for adult patients. Potential drug- interactions were identified using the Drug Interaction Checker (Medscape®).Results: A total of 3066 doses were analyzed, with a concentration of 4 schedules, showing an institutional standardization of schedules. The omission error rate was 5.44%. Drug-drug interactions of moderate severity were more frequent, especially lopinavir/clonazepam and diazepam/tramadol combinations.Conclusion: Omission errors and interactions can be minimized with tools to support clinical decision and reconfiguration of the work process.
Highlights
Hospital drug therapy has the potential for incidents, it is necessary to identify situations that may compromise patient safety
Quanto às interações medicamentosas com risco moderado, significa que a interação resulta em exacerbação do problema de saúde do doente e/ou requer uma alteração na farmacoterapia (Lima & Godoy, 2017; Drug Interaction Checker, 2019)
Relativamente às limitações deste estudo, pode referir-se que, apesar do número expressivo de doses medicamentosas analisadas, os resultados obtidos não permitem generalização por serem obtidos em apenas duas unidades de internamento, podendo ocorrer resultados diferentes em outras realidades
Summary
Hospital drug therapy has the potential for incidents, it is necessary to identify situations that may compromise patient safety. O objetivo geral deste estudo é investigar as potenciais interações medicamentosas favorecidas pela sobreposição de medicamentos programados por enfermeiros nas prescrições de doentes numa unidade de internamento hospitalar.
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