Patient Characteristics and Outcomes of Extracorporeal Cardiopulmonary Resuscitation (ECPR) for Adult Non-traumatic Out-of-hospital Cardiac Arrest (OHCA) versus Non-ECPR – A community-wide evaluation

Abstract

between patients treated with ALS and BLS. Main outcome measures were functional status at 1 month after OHCA (good status defined as cerebral performance category 1 or 2, and poor as 3 or 4). Results: Of the eligible 158,991 patients, 148,230 (93.2%) were received ALS and 10,761 (6.8%) were received BLS. The propensityscore matching process selected 10,736 patients each from ALS and BLS group. Compared with BLS group, ALS group incurred a higher rate of return of spontaneous circulation before hospital arrival (8.6% vs. 6.2%) and poor functional status (3.4% vs. 2.5%), a similar survival rate (5.1% vs. 5.3%), and a lower rate of good functional status (1.7%vs. 2.8%). Inmultivariable logistic regression, ALS was associated with decreased odds of good functional status (odds ratio [OR] 0.56, 95% CI 0.42–0.74) and increased odds of poor functional status (OR 1.25, 95% CI 1.03–1.50). Adrenaline administration was also associated with decreased odds of good functional status (OR 0.41, 95% CI 0.25–0.67), meanwhile, no association was observedbetweenadvancedairway insertionand functional status. Conclusions: Among adult patients with OHCA in Japan, ALS was negatively associated with good functional status and increased the chance of poor functional survival compared with BLS.