Abstract
Current Global Initiative for Asthma (GINA) guidelines recommend a stepwise approach to asthma treatment. Patients recommended for step-up to biologics include those whose asthma is uncontrolled by high-dose inhaled corticosteroids/long-acting beta-agonists. We examined prior GINA step (GS), exacerbations, and asthma control among patients escalated to biologics during the 12-months prior to escalation.
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