Pathology Phenotyping of Transgenic Mice for Modelling Human and Animal Diseases

Abstract

During the last 30 years, spontaneous mutations in mice mimicking a wide variety of human diseases have been collected for research purposes. The use of genetically engineered mice has been considered one of the most important advances of the 1990s, the so called decade of the mouse, that will clearly improve in the twenty-fir st century taking into account the biomedical research revolution in technology.