Abstract
Takotsubo (ampulla) cardiomyopathy is characterized by slight to moderate elevation of cardiac enzymes. It is reasonable to think that the elevated levels are evidence of myocardial damage (cardiac-specific enzymes are released from the cytoplasm of damaged cardiac myocytes into extracellular fluid). Thus, it is problematic to consider takotsubo cardiomyopathy as (neurogenic) stunned myocardium, because stunned myocardium is defined as a state without histopathological changes observable by light microscopy.1 In the study, I will describe histological findings in autopsied cases in Japan and histopathological findings of endomyocardial biopsy cases with a literature review.
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