Abstract

A study was conducted to assess pathological changes in endocrine glands induced by 1 and 1.5 ppm dietary levels of aflatoxin (AF) in Athulya layer birds fed for 21 days. The control and AF fed layer birds did not show any clinical signs and mortality except for irregular areas of calcium deposits on egg shell surface. The histopathological alterations included basophil depletion and acidophil prominence in the pituitary and diffuse capsular thickening, hypercellularity of cortical areas and multiple cytoplasmic vacuolation of cortical cell in adrenal glands. The sections of thyroid gland showed pale and thinner colloid mass in the follicles and interfollicular congestion. The histopathological alterations in the present study could be attributed to indirect hepatotoxicity of AF.

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