Abstract
The leiomyosarcoma is a tumor of mesenchymal origin of smooth, malignant, slow-growing muscles. The present study reports a case of duodenal leiomyosarcoma in Labrador dog. A 6 year old black female Labrador dog with history off feed, vomition and melena brought for necropsy examination. Gross lesions revealed tennis ball size tumorus mass at the initial portion of duodenum resulting into the obstruction of intestinal lumen. Microscopically, duodenum with tumours mass revealed smooth muscle bundles arranged in all the directions having elongated blunt ended nuclei along with numerous blood vessels and mitotic figure which is indicative of leiomyosarcoma.
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