Abstract
Epithelial ovarian cancer (EOC) is categorized into two pathological subtypes, such as EOC Ⅰ and Ⅱ subtype, with distinct origins and malignant phenotypes. However, EOC presents heterogeneity in diverse aspects like pathological morphology, clinical feature, molecular phenotype, etc.. With increasing data based on second-generation gene sequencing technology, we have deepened our understanding of the biological behaviors of EOC. The comprehensive diagnosis of pathological and molecular characteristics may provide more efficient and accurate screening and treatment strategies for EOC. This paper focuses on the development of EOC′s pathological and molecular diagnosis mechanism and the technology of molecular diagnosis, as well as the latest research progress in the application of EOC screening and treatment. Key words: Ovarian neoplasms, epithelial; Molecular targeted therapy; Phenotype; Genetic heterogeneity; Histocompatibility testing; Molecular diagnostic techniques; Second-generation gene sequencing technology; Female
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