PATHOLOGICAL AND BIOCHEMICAL STUDY OF ACUTE FASCOILiOSIS IN CATTLE SLAUGHTERED AT KIRKUK ABATTOIR, KIRKUK, IRAQ

Ahmed S Sultan

doi:10.21608/avmj.2019.168954

Abstract

Liver fluke disease (fascioliosis) is an important parasitic disease may accountable for morbidity and mortality in most species of animals, like cattle, sheep and goat as well as other domestic ruminants. It occurs worldwide due to infection with liver fluke species. The study aimed to notice the gross, microscopic lesions and measured serum biochemical changes accompanied with acute bovine liver Fascioliosis of cattle in Kirkuk. From March to April 2018, fifteen infected bovine livers of different ages were collected from Kirkuk abattoir, and examined grossly. A noticeable rise in the level of serum AST, ALP and also ALT were observed. In gross examination several short vermiform cords were observed on the hepatic surface and the surface had a rough appearance. Some immature, wandering flukes were noted on the cut surface. Histopathologically, a wide range of liver lesions were found. The most important lesions were moderate to severe perihepatitis and haemorrhagic tracts on the hepatic surface. These lesions related to migratory channels filled with blood, fibrin and cellular debris. The present study results indicated that serum biochemical alterations were consistent with pathological lesions; hence the analysis of serum biochemical could be used in diagnosis of acute bovine fasciolosis with other tests.

Highlights

Liver fluke infection was caused by Fasciola hepatica and F.gigantica and it remains economically important parasite of livestock and is emergent zoonotic infection
The study's objectives were to measure pathological variations of the liver, hepatic lymph nodes and gall bladder; to assess serum biochemical variations associated with acute infection with liver fluke, and to start association between pathological changes and serum biochemical parameters of the cattle liver
Fifteen samples from acute bovine liver Fascioliasis at different ages were collected after examination of livers grossly, palpation, incision and noted any changes which detected in the tissue texture of hepatic parenchyma and bile duct

Summary

INTRODUCTION

The migratory tracts formed by migrating of immature flukes through the hepatic parenchyma were seen as tracts of necrosis (Steyl, 2009). The tests of serum biochemical including enzymes of serum liver are supportive to evaluate the severity of injury of hepatic cells and to monitor the evolution of the disease in animals (Lee et al, 2005). The analysis of serum biochemical used to assess the degree of cholestasis and the capacity synthesizing of the liver (Hodzic et al, 2013). The study's objectives were to measure pathological variations of the liver, hepatic lymph nodes and gall bladder; to assess serum biochemical variations associated with acute infection with liver fluke, and to start association between pathological changes and serum biochemical parameters of the cattle liver

MATERIALS AND METHODS

RESULTS

Findings

CONCLUSION AND RECOMMENDATIONS