Pathologic reflexes of proximal /INS;segments in ALS patients

Abstract

Introduction: Amyotrophic Lateral Sclerosis is a neurodegenerative disease that affects both motor cortex and anterior horn motoneurons producing a progressive amyoatrophy of all voluntary muscles including the ones innervated by the cerebral bulb. The atrophy progresses /INS;from the distal muscles of the limbs to the central ones, this is clearly detected by an electromyography study. The hyper /INS;reflexia of ankles, knees, wrists and elbow are pathognomonic signs of cortical liberation of the spinal cord reflex arches.