Abstract
Initial combination drug regimen containing cis-platin in patients with head and neck cancer produced a high percentage of clinical response. Despite numerous trials showing high tumor response rates, a survival advantage resulting from the use of chemotherapy has yet not been demonstrated conclusively. This trial was initiated to study the cytotoxic effect of chemotherapeutic agents on squamous cell carcinomas. 31 patients with oropharyngeal carcinomas received prior to surgical resection a polychemotherapy consisting of cis-platin and bleomycin. After surgical tumor resection the histopathologic examination based on the serial sections of the tumor tissues and neck dissection blocks showed no case of complete tumor response. Even in 9 patients with complete clinical tumor response the histopathological investigation revealed tumor cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
