Pathognomonic neuroimaging of a Multinodular and Vacuolating Neuronal Tumor of the Cerebrum incidentally discovered in an 8-year old female. A case report

Abstract

Background. The WHO 2016 classification of tumors of the CNS includes Multinodular and Vacuolating Neuronal Tumors (MVNT) as a benign ganglion cell tumor, possibly associated with seizures. MTVN pathologic hallmark to be consisting of a “subcortical cluster of nodular lesions located on the inner surface of an otherwise normal appearing cortex, within the deep cortical ribbon and superficial subcortical white matter”. MVNT is mostly present in adults. Case report. In this case, we report pathognomonic pics of MVNT in a noticeably rare young patient, where it was unclear whether MVNTs should be considered a true neoplasm or malformative lesion, that typically occurs causing seizures Conclusion. It confirms nowadays that in clinical practice the MRI can help neurosurgeons to confirm the clinical non-surgical diagnosis even if in the lack of more common symptoms such as seizures.