Abstract
Pathological characteristics of six reoviruses, strains 56-168, 57-F, 56-93L, 57-161, 56-256T3 and 57-162 isolated from leg-tendon materials, were compared upon infection of day-old specific-pathogen-free chicks by the footpad or oral routes. The chicks were examined for clinical signs, body weight, gross lesions of footpad, microscopic lesions of tendon sheaths, virus recovery and AGP antibodies after inoculation. An apparent leg-weakness or lameness was not produced throughout the experiment by any reovirus inoculation, while growth retardation and abnormal feathering were observed mainly in footpad inoculated chicks. Considerable variations in the gross and microscopic lesions and virus recovery rates were recognized among six reoviruses. Strains 56-168, 57-F and 56-93L produced distinct tenosynovitis by either footpad or oral inoculations, moreover, they were recovered from the lesions at 35 days of age. Strain 57-162 could not induce tenosynovitis by not only oral but also footpad inoculation.
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Schedule a callMore From: Nihon juigaku zasshi. The Japanese journal of veterinary science
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