Abstract
Jurajda V., R. Halouzka: Pathogenicity of a Field Marek's Disease Virus Isolate (VUB-83) for Chickens of Three Genetically Different Types. Acta vet. Brno, 58,1989: 273-279. The incidence of Marek's disease (MD) after parenteral infection of chickens of three genetically different types (Hybro pullets, final White Hisex hybrids and Brown Leghorn chickens) with a field isolate (VUB-83) of MD virus was followed under laboratory conditions. MD was diagnos ed on the basis of gross lymphomas or, in their absence, on the basis of histological examination in chickens that died during the 105-day observation period. The incidence of MD lymphomas in chickens that died and the mean time to death showed significant differences between the three groups in the following order: Hybro (95.8 %; 78.1 days), Hisex (75 %; 55.5 days) and BrL (57.2 %; 43.1 days). Total mortality and the incidence of MD was lowest in Hybro pullets (63.2 % and 68.4 %), differing significantly from the values observed in Hisex (94.1 % and 94.1 %) and BrL (95.6 % and 100 %) chickens. The total incidence of MD lymphomas showed no significant differences between the three groups (Hybro, 65.8 %; Hisex, 70.6 %; BrL, 53.3 %). In all the chickens tested the most frequently tumour-affected organs after infection with isolate VUB-83 were the liver (34.7 %) and the spleen (29.5 %). The early mortality syndrome was not observed.
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