Abstract

Pathogenicity and Immunogenicity of Attenuated Fowl Adenovirus from Chicken Embryo Liver Cells in Commercial Broiler Chickens

Highlights

  • Fowl adenovirus (FAdV) is non-enveloped DNA virus which has been classified into five molecular species (A-E) and 12 serotypes

  • Detection of FAdV antibody titre The FAdV antibody titre was determined by commercial Enzyme Linked Immunoabsorbent Assay (ELISA) kit (BioChek, UK)

  • The microtitre plate coated with Fowl adenovirus group 1 (FADV Gp1) antigen was added with 100μl of negative and positive control into respective wells as described in the protocol

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Summary

Introduction

Fowl adenovirus (FAdV) is non-enveloped DNA virus which has been classified into five molecular species (A-E) and 12 serotypes. FAdV mostly infect broiler chickens at age 3 to 6 weeks old and is readily transmitted both horizontally by the fecal-oral route and vertically by embryonated eggs (Shah et al, 2017; Pan et al, 2017). FAdV infection caused several clinical diseases in avian species such as inclusion body hepatitis (IBH), gizzard erosion, hydropericardium syndrome (HPS), necrotizing pancreatitis and respiratory disease (Kajan et al, 2013; Okuda et al, 2004; Balamurugan and Kataria, 2004). Among 12 serotypes of FAdV, May 2021 | Volume 9 | Issue 5 | Page 648

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