Abstract

The review summarizes the data of foreign studies on the relationship of the taxonomic diversity of the oral microbiota and changes in its composition with the development of the metabolic syndrome in children with obesity. This information is of scientific interest from the point of view of the search for new targets and possible ways of conservative treatment in order to prevent and treat obesity through maintaining the microflora of the gastrointestinal tract.

Highlights

  • The review summarizes the data of foreign studies on the relationship of the taxonomic diversity of the oral microbiota and changes in its composition with the development of the metabolic syndrome in children with obesity

  • This information is of scientific interest from the point of view of the search for new targets and possible ways of conservative treatment in order to prevent and treat obesity through maintaining the microflora of the gastrointestinal tract

  • В связи с актуальностью поиска новых терапевтических мишеней для профилактики и коррекции компонентов формирующегося с детства метаболического синдрома, изучение состава и метаболической активности микробиоты пищеварительной системы, начиная с полости рта, в аспекте связи с развитием ожирения, возникновением дисгликемии и нарушений пищевого поведения, представляет научный интерес и требует накопления большего количества данных для последующего обобщения и анализа с точки зрения их практической значимости

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Summary

Introduction

The review summarizes the data of foreign studies on the relationship of the taxonomic diversity of the oral microbiota and changes in its composition with the development of the metabolic syndrome in children with obesity. Патогенетическая взаимосвязь микробиоты ротовой полости и ожирения у детей и подростков. На современном этапе изучается состав микробиоты не только кишечника, но и других биотопов (локусов) в организме человека, и появляются все больше работ, в которых исследуется связь изменения микробиома полости рта с развитием ожирения [5].

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