Abstract
Purpose. To summarize and systematize the literature data on the pathogenetic aspects of the influence of seasonality on the health status of patients with chronic pathology of the cardiovascular system.
 Materials and methods. To analyze the literature, materials from the PubMed and PubMed Central resources of the US National Library of Medicine, Google Scholar, Elsevier Clinical Key and Elsevier Science Direct, as well as in the Russian RSCI database were used. The sample consisted of scientific papers devoted to the pathogenetic aspects of the influence of various meteorological factors on the course of cardiovascular pathology.
 Results. The generalized results of clinical and experimental studies presented in this review indicate both direct and indirect effects on the state of the cardiovascular system of seasonal changes in air temperature, atmospheric pressure, solar radiation, air humidity and geomagnetic indicators.
 Conclusion. Meteorological factors have a pronounced effect on the course of cardiovascular diseases both through direct mechanisms of influence, and through the inclusion in the pathogenesis of these diseases and the aggravation of existing risk factors. The pathogenetic mechanisms of the influence of weather factors on the state of the cardiovascular system are important for understanding the application points that can be influenced and improved by primary and secondary prevention of cardiovascular pathology.
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