Abstract
The obesity epidemic in the 21st century is an actual public health problem. The obesity is the cause of many pathological conditions in humans. According to the latest data there is a link between reproductive health and obesity, in particular, with a decrease in the quality and quantity of ejaculate in men. Nevertheless information about the effect of obesity on the parameters of spermogram is controversial. The purpose of this review was to study the relationship of body mass index with sperm parameters in animal experiments and indicators in men of reproductive age. This article reviewed the results of studies conducted on animals, as well as systematic reviews of studies conducted in a clinical setting.
Highlights
The obesity is the cause of many pathological conditions in humans
According to the latest data there is a link between reproductive health and obesity, in particular, with a decrease in the quality and quantity of ejaculate in men
This article reviewed the results of studies conducted on animals, as well as systematic reviews of studies conducted in a clinical setting
Summary
Изучение роли избыточного веса и ожирения в развитии субфертильности у мужчин весьма актуально, поскольку в репродуктивном возрасте значительное количество пар имеют избыточный вес и ожирение [3]. Данные литературы свидетельствуют о негативном влиянии рациона с высоким содержанием жиров на объем эякулята животных, количество, морфологию и подвижность сперматозоидов, а также на их фертильность. Что ожирение вызывает изменение содержания микроРНК сперматозоидов и снижение метилирования ДНК в половых клетках на 25 %.
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