Abstract
In this work we propose a pathogenic classification of hypercholesterolemia based on the genes involved, these mainly for the health public. Are dividing into non-syndromic forms where we group the variants in seven genes LDLR, APOB, PCSK9, ABCG5, ABCG8, ARH, CYP7A1. And the syndromic forms are dysmorphological pathologies where hypercholesterolemia is secondary, due to variants in the genes that code for G6Pase, PBK, AGL, JAG1, NPHS1, MYH9, APTX, TDP1, TTPA, WRNQ, CSB, and the ABCG9 gene. In public health, the study of syndromic forms of hypercholesterolemia shows genes not directly related to cholesterol metabolism, which must be ruled out in the molecular profile of the patient and at the population level.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Advanced Multidisciplinary Research and Studies
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
