Abstract

Hydroxyapatite can occur in joints and must be suspected to be the explanation for some acute arthritis and exacerbations of osteoarthritis. Clumping of the tiny crystals may be needed to produce phlogistic particles. The granular material around the crystals may also be important as has been proposed in gout and pseudogout. Recent identification of this proposed new cause for crystal-induced arthritis should encourage search for patients with other crystals that might cause synovitis such as the calcium hydrogen phosphate dihydrate crystals known to occur in menisci (McCarty et al, 1966) and suspected in one effusion by Skinner and Cohen (1969).

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