Abstract
Aortic stenosis is a common heart valve disease. Among adults, the most crucial cause of aortic stenosis is aortic valve calcification. Recent studies have shown that several factors may efficiently lead to aortic valve calcification such as age, valve structure, metabolism and genes. Although the main treatment for aortic valve calcification is still via surgery, with the further and deeper investigation in pathomechanism of aortic stenosis, we have made progress in pharmaceutical therapy for aortic valve stenosis patients. This article mainly focuses on the pathogenesis and treatment of calcified aortic valve stenosis. Key words: Heart valve disease; Aortic valve stenosis; Pathology; Therapeutics; Review
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