Abstract

Synovial sarcoma of the nasal cavity and sinus are rare,comprise less than 0.1% of all soft tissue malignancies. Synovial sarcoma is a malignant mesenchymal tumor with variable epithelial differentiation, which is defined by the presence of a specific chromosomal translocation that generates SS18-SSX fusion oncogenes. The treatment include surgery,radiotherapy,chemotherapy. As the delicate anatomy of the nasal cavity and sinus limits the ability to obtain wide surgical margins. This maybe the reason why there is a higher local recurrence rate and worse disease-specific survival in head and neck sarcomas compared to other sites.

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