Abstract

Chronic rhinosinusitis (CRS) is divided into CRS with nasal polyp formation (CRSwNP) and CRS without NP formation (CRSsNP) according to the phenotype classification. CRS is also divided into type 1/type 2/type 3 according to the endotype classification. CRSwNP and type 2 CRS are caused by eosinophilic inflammation in most cases, and are intractable. Useful biomarkers for such cases of eosinophilic CRS (eCRS) are desired for predicting their severity and postoperative courses.

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