Abstract
This review summarises patents from 1999 to 2002, claiming compounds and methods for antimicrobial agents effective against pathogenic fungi of the genus Candida. The majority of the patents described in this review will focus on modifications or novel compounds of the three major classes of antifungal agents currently approved for human use against Candida infections; polyenes, azoles and cell wall synthesis inhibitors. Novel compounds and approaches will also be considered. Since the correlation between antifungal effects in vitro and efficacy in vivo is often not strong with antifungal agents, emphasis will be placed on filings for which biological data in animal models has been disclosed.
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