Abstract
Background: Patent ductus arteriosus (PDA) is the common congenital heart disease that needs medical attention to deal with disease related complications. With the advancement of transcatheter intervention closure of PDA by coil or Amplatzer devices, has become acceptable alternate to surgical ligation.
 Methods: This retrospective study was conducted (from January 2014 to December 2016) and data were collected from records of Pediatric cardiology department of BSMMU. Fifty children were included in the study. All the cases were assesed with 2D echocardiography, Color Doppler echocardiography (CDE) and angiography and underwent device closure. Estimation of PDA size were done with 2D, color doppler and angoigraphically and were compared and analysed statistically.
 Results: Out of 50 cases, ages ranged from 10 months to 28 years with a mean age of 5.75 ± 5.33 years. The mean weight was 16.3 ± 10.58 Kg with a range of 5.5 Kg to 54 kg and sex distribution was 16 males and 34 females. Visualization of the patent ductus arteriosus was achieved from short-axis and suprasternal-axis views in all children with CDE. The mean diameter of pulmonary end of patent ductus arteriosus was 3.45 ± 0.96 millimetre with a range from 1.45 to 6.20 millimetres in CDE. The mean diameter of aortic end of PDA 4.64±1.30 with a range of 2.50 to 9.50 in 2D and CDE respectively. The mean angiographic measurement of aortic end of PDA was 5.35±1.42 with a range of 2.60 to 10. Both 2D echo and CDE correlated significantly (p value <.0.001) with angiographic measurement at both pulmonary and aortic ends. The pearson correlation coefficient for 2D echo and CDE are 0.967 and 0.973 respectively at pulmonary end indicating that CDE correlates marginally better than 2D echo with angiographic measurements at the pulmonary end. Similarly at the aortic end (ampulla), the Pearson correlation coefficient for 2D echo and CDE are 0.955 and 0.966 respectively indicating that both correlates with angiography but CDE is better correlates. 
 Conclusion: We may conclude that it is almost always possible to measure the dimensions of the patent ductus arteriosus with colour Doppler echocardiography. But we should keep in mind color doppler echocardiographic measurement overestimates the angiographic measurement of the pulmonary side of the patent ductus arteriosus and underestimates its aortic side, which should be considered for the measurement of the size of the patent ductus arteriosus.
 Bangladesh Med Res Counc Bull 2019; 45: 11-16
Highlights
One of the most common congenital cardiac condition in pediatric patients is patent ductus arteriosus, and recently assumed major importance as a life threating disease of small premature infants, who survive due to advances in neonatology.[1,2,3,4] Alternative to the surgical ligation, The device selection is typically based on ductal morphology and dimensions
It may concluded that it is almost always possible to measure the dimensions of the patent ductus arteriosus with colour doppler echocardiography, keeping in mind that color doppler echocardiographic measurement overestimates the angiographic measurement of the pulmonary side of the patent ductus arteriosus and underestimates its aortic side
At the aortic end, the Pearson correlation coefficient for 2D echo and color Doppler are 0.955 and 0.966 respectively indicating that both correlates with angiography but color Doppler echo (CDE) is better correlates
Summary
One of the most common congenital cardiac condition in pediatric patients is patent ductus arteriosus, and recently assumed major importance as a life threating disease of small premature infants, who survive due to advances in neonatology.[1,2,3,4] Alternative to the surgical ligation, The device selection is typically based on ductal morphology and dimensions. PDA Size estimation measurements and, device selection may result in adverse events, including systemic or pulmonary embolisation, incomplete ductal closure and haemolysis. With the advancement of transcatheter intervention closure of PDA by coil or Amplatzer devices, has become acceptable alternate to surgical ligation. Objects: The study was aimed estimation of size of patent ductus arteriosus by 2D and colour Doppler echocardiography and to compared with the data obtained by angiography
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
