Patent Blue Dye: Allergen Increasing

Abstract

Patent blue dye (PBD) is one of the most used dyes to identify the sentinel lymph node during breast cancer surgery. It is estimated as the culprit in 5% of peri-operative anaphylaxis. We present two cases of peri-operative anaphylaxis. The first, it is a 62 year old woman who presents a widespread violaceous wheal eruption immediately after anesthetic induction and dye infiltration. The second, it is a 69 year old woman who presents, after 20 minutes of the surgery beginning, abrupt hypotension refractory to treatment and forehead and hands angioedema.