Abstract

Objective: To invesitigate 3-year patency rate of autogenous arteriovenous fistula(AVF)in the patients with late fistula dysfunction/failure. Methods: The prospective study was carried out in the First Hospital of Tsinghua University from March 2012 to March 2013. A total of 136 maintenance hemodialysis patients with late AVF dysfunction/faliure who received AVF repairment were enrolled in the study. All the patients were divided into three groups according to surgical procedures: venous neointimal hyperplasia (VNH) stripping group (group A), non-VNH stripping group (group B) and creation of a new AVF group (group C). Patency rate was calculated by survival analysis method, and survival curve of fistula was drawn as well. Results: During 12-36 months follow-up, there were 46 patients with late AVF dysfunction/faliure in group A, 38 patients in group B, and 52 pateints in group C. The AVF patency rate was 88.6% at 12th month, 77.6% at 24th month, and 57.2% at 36th month in group A; 89.3% at 12th month, 74.5% at 24th month, and 55.1% at 36th month in group B; 88.1% at 12th month, 76.8% at 24th month, and 59.0% at 36th month in group C. The AVF patency rates had no statistical difference among three groups at three time points (12th, 24th and 36th month) (P>0.05). Conclusion: The patency rate was high in the patients who recieved AVF repairment. There was no significant difference in the patency rate among three different surgical treatments.

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