Abstract
Osteosarcoma is the most common histological form of primary bone cancer. It is an aggressive malignant neoplasm arising from primitive transformed cells of mesenchymal origin that exhibit osteoblastic differentiation and produce malignant osteoid. The most common form of treatment is removal of the lesion. Limb-sparing procedures can often be used to preserve function. Chemotherapy is also required to treat micrometastatic disease, which may be present, but not detectable in most patients at initial diagnosis. We present a proximal anteromedial tibial metaphysical Osteosarcoma in a 51 year-old adult male. Diagnosis was confirmed by radiography and histopathology. Pre-up palliative care, en bloc resection of the tumor with the patella and iliac graft reconstruction and post-operative chemotherapy were performed. After multi-step surgeries, the patient made full clinical and symptomatic recovery. Further 4 and 10 years follow ups revealed a
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