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Abstract
The purpose of this article review was to find out more about acne patch formulations and test stability. The method used is searching data from various articles based on Google Scholar, Elsevier, and Molecules with the keywords "Acne vulgaris, acne treatment, acne patches, and types of acne patches” and with a range of years between 2011 and 2021. Based on the type of acne, acne patches are divided into several types, namely microneedle patches, acne medicine patches, and hydrocolloid patches. The results obtained in this review show that the most commonly used acne patch is the medicated acne patch (hydrogel patches), because of its waterproof property to protect acne from secondary infection, it can absorb liquid inside and flatten acne and is cheaper compared to microneedles. The hydrogel patch is also stable at a temperature of 40±2 °C and a relative humidity (RH) of 75±5% for 6 mo of storage.
Highlights
Acne vulgaris is an inflammatory disease that occurs in the sebaceous unit of the hair follicle
Acne patches on the market are usually made of hydrocolloids or hydrogels; these substances are known for their use in medical dressings
In a study by Zhang et al 2020 Microneedle patches were made from poly (PILs) as a base material, which is a group of polymers derived from ionic liquid monomers (IL) and has high physical and chemical stability
Summary
Acne vulgaris is an inflammatory disease that occurs in the sebaceous unit of the hair follicle. Oral antibiotics are given to patients with moderate to severe acne severity and in patients with inflammatory acne that is resistant to topical treatments oral antibiotics show better therapeutic efficacy, their use should be limited because they can cause inflammatory bowel disease, pharyngitis, induction of Candida vulvoganitis, and Clostridium difficile infection. Acne patches on the market are usually made of hydrocolloids or hydrogels; these substances are known for their use in medical dressings.
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