Abstract
In contrast to type I allergy, there is an ongoing debate about the relationship between delayed-type allergy (type IV allergy) and atopic eczema (AE) and on the issue of whether patients with AE are more or less prone to (occupational) delayed-type contact allergy. Whenever patch testing is done, a reliable diagnosis of AE has to be settled, and all patients have to be assessed by a combination of detailed clinical examination and anamnestic questions. According to recent publications, contact allergy to occupational and nonoccupational allergens is at least as common in AE patients as in non-AE patients. Therefore, patients with AE should be patch tested because they also develop contact allergy to a significant degree. Patch testing often adds valuable information about contact allergy in AE patients.
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