Abstract
The admittance of the resting membrane of squid axon is investigated in natural and artificial seawater with alternating currents using an internal axial electrode. Corrections for the series electrolyte resistance between electrodes and membranes were applied to the measured admittance and the membrane capacitance and conductance are calculated. The membrane capacity was found to decrease from 1 μF/cm2 to about 0.6μF/cm2 between 1 kHz and 50 kHz. The conductivity was found to increase from 1.2 mmho/cm2 to 40 nmho/cm2 in the same frequency range. In addition to the capacitive and conductive components, and inductive element is observed at low frequencies confirming the early work by Cole and co-workers. The effect of tetrodotoxin (TTX) and tetraethylammonium (TEA) on the membrane admittance was investigated. It was found that TTX did not have any effect on the capacitive component but has a profound effect on the inductive element. TEA alters the inductive element even more drastically than TTX.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
