Year-end Sale % OFF 
Abstract
Coagulation monitoring relies on in vitro tests where the clot formation is induced using external stimuli. We report an optical method capable of revealing the propensity of coagulation based solely on the natural dynamics of erythrocytes in whole blood. In contrast to traditional techniques, our approach provides means to assess the blood coagulability without the need to chemically trigger the coagulation. Results of correlations with standard clinical methods suggest that this optical assay could be used for continuous management of blood coagulation during clinical procedures.
Highlights
Coagulation is a factor activation cascade process that results in the formation of a blood clot.It takes place both during hemostasis, the natural cessation of blood loss after a vessel is damaged, as well as in pathological thrombosis, where a thrombus forms inside a vessel [1,2]
The results of this study demonstrate that a continuous dynamic light scattering measurement is able to discriminate between subtle differences in the initial coagulation stages of blood in
The results of this study demonstrate that a continuous dynamic light scattering measurement is able toHemato discriminate subtle differences in the initial coagulation stages of blood in untreated
Summary
Coagulation is a factor activation cascade process that results in the formation of a blood clot It takes place both during hemostasis, the natural cessation of blood loss after a vessel is damaged, as well as in pathological thrombosis, where a thrombus forms inside a vessel [1,2]. Assessing the coagulation status of blood is critical for managing the blood condition during a variety of clinical procedures. These include cardiovascular surgeries requiring cardiopulmonary bypass (CPB), major surgeries in patients with coagulation disorders, extracorporeal life support (ECLS, ECMO), catheter-based interventional procedures, and hemodialysis, among others [4]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
