Abstract
The purpose of this study was to determine the pattern of drug use, potential interactions, and side effects of antiplatelet drugs in acute myocardial infarction patients in inpatient installations to reduce morbidity and mortality rates at Gambiran Hospital, Kediri City. This study is a non-experimental study with descriptive research design and retrospective data collection, data collection using purposive sampling method. Retrospective data collection based on medical record data of patients with acute myocardial infarction, this research was conducted from January to December 2020, so that the pattern of use of anti-platelet drugs in patients with acute myocardial infarction was a combination of aspirin 80 mg 1x1 with clopidogrel 75mg 1x1 (93%), with the route of drug administration orally. Analysis of potential drug interactions was carried out using the Drugs Interaction Checker and obtained 4 occurrences of major potential interactions and 10 occurrences of moderate potential interactions. The desired potential drug interaction was to prevent platelet aggregation. There was an undesirable potential drug interaction related to decreased antihypertensive effect of the drug, while potential drug interactions in the form of gastrointestinal bleeding and decreased renal function could not be determined.
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