Partition of solutes into wet and dry ethers; an LFER analysisElectronic supplementary information (ESI) available: tables of solute descriptors and log P values. Values of log Kw and L. See http://www.rsc.org/suppdata/nj/b3/b303016d/

Abstract

Equations based on the Abraham solvation equations are presented for the partition of solutes between water and wet diethyl ether, wet diisopropyl ether, dry diethyl ether, dry diisopropyl ether, dry tetrahydrofuran and dry dioxane, and between the gas phase and wet diethyl ether, dry diethyl ether, dry tetrahydrofuran and dry dioxane. These equations can be used to predict further partition coefficients, and also provide information on the chemical features of the various systems. It is shown that wet diethyl ether is more basic and less hydrophobic than dry diethyl ether, although the differences are quite small. The hydrogen bond basicity of dry tetrahydrofuran and dry dioxane is about the same as that of wet diethyl ether and wet diisopropyl ether, and their hydrophobicity is between that of wet and dry diethyl ether.