Abstract
The application of reversed phase high performance thin layer chromatography has been evaluated for determination of octanol-water partition coefficients (P oct) of organic chemicals. Best correlations between log P oct and R M-values were obtained on a C 18-bonded stationary phase using acetone-water or acetonitrile-water mixtures as eluting solvent. The latter mixture is preferred in work with high pressure liquid chromatography. A number of aryl and alkyl/aryl phosphate esters, polychlorinated paraffins and chemicals suggested as PCB-substitutes were chromatographed and the corresponding log P oct-values calculated. Values for the phosphate esters corresponded reasonably well with previously reported data while data for other, often more complex compound mixtures ( eg PCB-substitutes), need further evaluation. The use of the chromatographic system for screening purposes in work on environmentally significant data of possible organic pollutants is discussed.
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