Abstract
The infective principle of ribonucleic acid (RNA) isolated from tobacco mosaic virus (TMV), either by Duponol C or water-saturated phenol, has a sedimentation constant of 19·6 Svedberg units at 5°C in 0·02 M -phosphate, pH 7·3, as determined by partition cell ultracentrifugal analysis. This corresponds to an S 20 of 30. In fresh samples of RNA, the bulk of the material has the above sedimentation rate. The weight average molecular weight of such samples is 2 × 10 6 as determined by light scattering. The sedimentation rate of the infective principle in samples degraded at room temperature to various fractions of residual activity remains the same, although the bulk of the material sediments at a much slower rate. It is therefore concluded that the smaller components do not carry a detectable amount of the infectivity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
