Abstract

The particles from gas-saturated solutions process was performed to micronize lecithin isolated by ethanol from deoiled mackerel by Supercritical Carbon Dioxide (SC-CO2). The particle formation of lecithin with biodegradable polymer, polyethylene glycol (PEG) was carried out by PGSS process using SC-CO2. Conditions were optimized by applying different temperatures (40 and 50°C) and pressures (15-30MPa) for PGSS process for 1 hr. The particles were characterized by scanning electron microscope (SEM) and Particle size analyzer (PSA) to determine their shape. The average diameter of lecithin particle was high at higher temperature and pressure. The average diameter of the particles was about 0.37-2.42μm. The inclusion of lecithin in PEG was qualitative measured by HPLC.

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