Abstract
Enhancement of interferon production in mouse peritoneal macrophages by Newcastle disease virus (NDV) under-neutralized with whole antiserum or its IgG fraction was inhibited in cells pretreated with iodoacetamide, sodium nitrite or formaldehyde, which blocked adsorption of cytophilic antibody to macrophages. Mouse embryo primary culture cells had no receptor for cytophilic antibody, and in such a cell culture, under-neutralized NDV did not enhance interferon production. Antiserum enhanced interferon production by NDV which had adsorbed to cell surfaces, but did not affect NDV that had penetrated the cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
