¿Participa la serotonina cerebral en la memoria del aprendizaje incrementado?

Abstract

Normal 0 21 false false false ES-MX X-NONE X-NONE This is a brief review about the involvement of serotonin in memory consolidation. The available experimental evidence strongly suggests that, indeed, this biogenic amine participate in the storage of information derived from negatively-reinforced learning. However, the vast majority of experiments in this area of research has been carried out using systemic administration of drugs that interfere with serotonergic activity; thus, there is not a clear idea about which neural structures, which have serotonergic receptors, are involved in consolidation. Recent studies indicate that 5-HT2-type receptors of the striatum are important for memory and that in conditions of enhanced learning serotonin is not necessary for the development of learning and memory.