Abstract
The syntheses of 2,3,4-tri-O-acetyl(benzoyl)-β-D-glucopyranosyl isothiocyanates ( 3, 4) from the corresponding acylated N-(2,2-diethoxycarbonylvinyl)-β-D-glucopyranosylamine are described. Reactions of 3 and 4 with phenacylamine hydrochloride yielded N-phenacyl-N′-(2,3,4-tri-O-acyl-β-D-glucopyranosyl)thioureas ( 6, 7) whereas treatments of the same compounds with aminoacetone hydrochloride gave the N-nucleoside analogues 5-methyl-1-(2′,3′,4′-tri-O-acyl-β-D-glucopyranosyl)-4-imidazoline-2-thiones ( 8, 9). The partially protected N-(2-thiazoline-2-yl)-β-D-glucopyranosylamine ( 10) and the thioureylenedisaccharide II were prepared from 4 and 2-chloroethylamine hydrochloride under different reaction conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
