Partially Decalcified Allogenic Bone Graft-In Fibrous Dysplasis Treatment

Abstract

Background: Fibrous dysplasia of the bone is an uncommon, congenital skeletal disorder, and it not inherited. Spontaneous resolution of fibrous dysplasia does not occur. There is no cure for fibrous dysplasia, and existing guidelines for the treatment are not universally accepted. Treatment for fibrous dysplasia generally consist from clinical observation in non-symptomatic cases to surgical intervention in symptomatic or severe cases. Method: This study evaluated the fibrous dysplasia patients in a series of ten cases, treated by curettage and filling of the cavity using partially decalcified allogenic bone grafts, prepared by partial decalcification with 0.6N Hydrochloric acid (HCl) of human bones. Result: In five cases graft was fully incorporated and healing was considered complete and in another five cases, healing was partial. There was no failure of graft in any case. Conclusion: Study shows that the results of treatment of fibrous dysplasia by decalcified allogenic bone grafts are favourable. Keywords: Fibrous dysplasia, Allogenic bone grafts, Partially decalcified allogenic bone, Bone graft, Cystic lesion