Abstract
BackgroundThis meta-analysis aimed to investigate the efficacy and safety of partial weight bearing (PWB) versus early full weight bearing (FWB) after uncemented total hip arthroplasty (THA).MethodsWe conducted a search in PubMed, EMBASE, The Cochrane Library, and Web of Science for randomized controlled trials (RCTs) and non-RCTs comparing PWB and early FWB after uncemented THA. Two authors conducted the selection of studies, data extraction, and assessment of risk of bias independently. A pooled meta-analysis was performed using the RevMan 5.3 software.ResultsSix RCTs and three non-RCTs met the inclusion criteria. The meta-analysis indicated that compared with PWB, the FWB group showed greater femoral subsidence at 3-month follow-up (MD = −0.12, 95% CI −0.22 to −0.01, P = 0.03). There were no significant differences in the hip Harris score at 1-year and 2-year follow-up (MD = 1.54, 95% CI −0.83 to 3.90, P = 0.20; MD = 0.08, 95% CI −1.19 to 1.34, P = 0.90, respectively), in femoral subsidence at 2-year follow-up and at two additional years of follow-up (MD = −0.03, 95% CI −0.31 to 0.25, P = 0.84; (MD = −0.02, 95% CI −0.37 to 0.33, P = 0.91, respectively). There were no significant differences in the incidences of bone ingrowth fixation, spot welds, and radiolucent lines.ConclusionsThis meta-analysis shows that early FWB in patients with uncemented THA could be safe and could not increase the incidence of postoperative complications.
Highlights
This meta-analysis aimed to investigate the efficacy and safety of partial weight bearing (PWB) versus early full weight bearing (FWB) after uncemented total hip arthroplasty (THA)
This meta-analysis shows that early FWB in patients with uncemented THA could be safe and could not increase the incidence of postoperative complications
Others have suggested that early postoperative full weight bearing would not affect the stability of the prosthesis but could shorten the rehabilitation training and prevent disuse osteoporosis, bedsores, hypostatic pneumonia, and other complications, and it was highly recommended that patients who accepted uncemented THA should perform early postoperative full weight bearing (FWB) activities [10, 11]
Summary
This meta-analysis aimed to investigate the efficacy and safety of partial weight bearing (PWB) versus early full weight bearing (FWB) after uncemented total hip arthroplasty (THA). Total hip arthroplasty (THA) has long been recognized as the most effective surgical method in the treatment of hip diseases. Some studies have proposed that the time of partial weight bearing (PWB) of patients with uncemented THA should last for 6 to 12 weeks [9, 10]. Others have suggested that early postoperative full weight bearing would not affect the stability of the prosthesis but could shorten the rehabilitation training and prevent disuse osteoporosis, bedsores, hypostatic pneumonia, and other complications, and it was highly recommended that patients who accepted uncemented THA should perform early postoperative full weight bearing (FWB) activities [10, 11]. The initial stability and bone ingrowth of the uncemented prosthesis would be affected by the design of the prosthesis, which could not
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